Inflammation in human early life targeting impacts on life-course health
Tender Summary
The TURUN YLIOPISTO in Belgium from Europe region has released this tender for Inflammation in human early life targeting impacts on life-course health The development of the human immune system in early life including in utero impacts the risks of several diseases later in life particularly immune-mediated diseases such as allergies asthma and autoimmunity Yet the mechanisms of early life immune imprinting have been poorly understood in humans due to the difficulty in obtaining samples and the challenges of deriving the most important data from small sample volumes available Furthermore these studies are complicated by the many simultaneous exposures with potential impact on developing immune cells colonising microbes and immune-microbe mutualism To better understand such interactions a combinations of large population studies with longitudinal data and long-term follow-up and more detailed studies in smaller sets of children will be needed Here we propose such a combined and interdisciplinary approach by intersecting multiple cohorts and existing biobanks applying state-of the art technologies for exposure analyses and immune system investigation This will enable us to understand the environmental factors shaping human immune systems early in life their mechanisms of action and impact on life-course health The specific objectives of INITIALISE are 1 to elucidate how exposures and genome impact gut microbiome host immune system and metabolism and how the interplay of these factors impact life-course health 2 to define the role of the maturation of the immune system as a mediator between exposures and life-course health Functional studies will be performed to test specific mechanisms of environmental factors differing among children with different health outcomes and their imprinting on developing immune cells 3 to perform a pilot clinical study targeting the immune system for personalised disease prevention 4 to set up a collaborative data science platform for the studies of early-life factors linked with life-course health with tender notice no. 101094099 published on 30 Jul 2026. The tender is due to expire on 31 Dec 2028. This tender is sourced from Cordis and is eligible for suppliers interested in Services furnished by social membership organisations. Interested bidders can obtain further information including complete bid documents or ways to participate by registering on Tender Impulse and referencing via Tender Impulse ID 14078577.
Tender Details
Tender NoticeTI Ref: 14078577
Tender Notice No
101094099
Tender Organisation
TURUN YLIOPISTO
Tender Sector
Tender Service
Worldwide
Tender Region
Tender Project Location
Tender CPV
98133000 : Services furnished by social membership organisations
Tender Source
Cordis
Tender Document Type
Tender Notice
Tender Deadline
31 Dec 2028 873 days left
Tender Description
Inflammation in human early life targeting impacts on life-course health The development of the human immune system in early life including in utero impacts the risks of several diseases later in life particularly immune-mediated diseases such as allergies asthma and autoimmunity Yet the mechanisms of early life immune imprinting have been poorly understood in humans due to the difficulty in obtaining samples and the challenges of deriving the most important data from small sample volumes available Furthermore these studies are complicated by the many simultaneous exposures with potential impact on developing immune cells colonising microbes and immune-microbe mutualism To better understand such interactions a combinations of large population studies with longitudinal data and long-term follow-up and more detailed studies in smaller sets of children will be needed Here we propose such a combined and interdisciplinary approach by intersecting multiple cohorts and existing biobanks applying state-of the art technologies for exposure analyses and immune system investigation This will enable us to understand the environmental factors shaping human immune systems early in life their mechanisms of action and impact on life-course health The specific objectives of INITIALISE are 1 to elucidate how exposures and genome impact gut microbiome host immune system and metabolism and how the interplay of these factors impact life-course health 2 to define the role of the maturation of the immune system as a mediator between exposures and life-course health Functional studies will be performed to test specific mechanisms of environmental factors differing among children with different health outcomes and their imprinting on developing immune cells 3 to perform a pilot clinical study targeting the immune system for personalised disease prevention 4 to set up a collaborative data science platform for the studies of early-life factors linked with life-course health
Tender Bidding Type
Tender Document
Frequently Asked Questions About This Tender
Who has issued this tender, and what is it for?
The tender has been issued by TURUN YLIOPISTO in Belgium. Such a type of tender falls under Services furnished by social membership organisations, within the Management Consultancy sector, and is listed on Tender Impulse under notice number 101094099.
What are the key dates for this tender?
The notice was published on 30 Jul 2026 and submissions close on 31 Dec 2028. Late bids are rarely accepted in public procurement, so aim to have your documents ready several days before the closing date.
Which CPV codes apply to this tender?
It is classified under CPV codes 98133000, which correspond to Services furnished by social membership organisations. If your company supplies these products or services, these are the codes to save in your alert profile so no matching tender passes you by.
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Is this tender beneficial for me?
The procurement is applicable to companies in the Services furnished by social membership organisations and related industries. If you belong to this industry, you can review the technical documents before assessing your relevance to your company.
What is the procurement trend for Inflammation in human early life targeting impacts on life-course health?
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